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Synthesis of halogenated analogs of 5-(4-chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]-isoindole or mazindol for exploration of the dopamine transporter

โœ Scribed by E Galinier; L Garreau; AM Dognon; JE Ombetta-Goka; Y Frangin; S Chalon; JC Besnard; D Guilloteau

Book ID
103629801
Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
726 KB
Volume
28
Category
Article
ISSN
0223-5234

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โœ E. Galinier; J. E. Ombetta; Y. Frangin; J. Mertens; J. C. Besnard; D. Guilloteau ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 467 KB

## Abstract The radiolabelling of an iodinated analog of mazindol, 5โ€(4โ€[^125^I]โ€iodophenyl)โ€2,3โ€dihydroโ€5โ€hydroxyโ€5Hโ€imidazo[2,1โ€a]isoindole, was performed in order to develop a potential tool for SPECT exploration of the presynaptic dopamine transporter in the human brain. Radiosynthesis was perf