Synthesis of glycyl-L-prolyl-L-leucyl-[14C(U)] glycyl-L-proline as a substrate for collagenase

✍ Scribed by Hung Lam-Thanh; Marie-Christine Heindl; Serge Fermandjian

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: French
• Weight: 241 KB
• Volume: 16
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580160607

✦ Synopsis

The synthesis of the ' 4C labelled peptide glycyl-L-proly1-L-

leucyl-' C ( U ) ]

glycyl-L-proline (I) with the specific activity of 50 pCi/mMole was performed by the Merrifield solid phase method. The peptide (I) was degraded by Achromobacter iophagus collagenase.