Synthesis of glycerol deuterated ether phospholipids
โ Scribed by Simone Nuss; Pierre Oudet; Luc Lebeau; Charles Mioskowski
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 107 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A method is described for the preparation of 1,2-dialkyl glycerol ethers starting from 3-tetrahydropyranyl-glycerol and alkyl methanesulfonates. By reaction of an excess of 1,2-dialkyl glycerol ethers and (l-14C)-alkyl methanesulfonares 14C-labelled trialkyl glycerol ethers are obtained in good yie
A series of new 2-[3-(2-alkyloxy-ethyl)-adamantan-1-yl]-ethoxy substituted ether phospholipids was synthesized and their antileishmanial activity was evaluated against Leishmania infantum amastigotes. The majority of the new analogues were significantly less cytotoxic than miltefosine while, antipar