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Synthesis of Gal-β-(1→4)-GlcNAc-β-(1→6)-[Gal-β- (1→3)]-GalNAc-α-OBn oligosaccharides bearing O-methyl or O-sulfo groups at C-3 of the Gal residue: specific acceptors for Gal: 3-O-sulfotransferases

✍ Scribed by Rakesh K. Jain; Conrad F. Piskorz; E. V. Chandrasekaran; Khushi L. Matta


Book ID
110244818
Publisher
Springer US
Year
1998
Tongue
English
Weight
148 KB
Volume
15
Category
Article
ISSN
1573-4986

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## Abstract Three trisaccharide derivatives of the type β‐D‐Hex__p__‐(1 → 4)‐β‐D‐Glc__p__NAc(1 → 2)‐α‐D‐Man__p__‐(1 → O)(CH~2~)~7~CH~3~ have been synthesized, with Hex being either glucose (15), 4‐deoxy‐4‐fluorogalactose (20), or 4‐deoxygalactose (27). These trisaccharides have been designed for th

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Synthesis of Protected Hexp-(1 → 4)-β-D-GlcpNAc-(1 → 2)-α-D-Manp-(1 → O)(CH2)7CH3 Sequences (Hex: β-D-Glc, 4-deoxy-4fluoro-β-D-Gal, or 4-deoxy-β-D-Gal) Using a Glc-GlcNPhth Donor, Eventually Fluorinated or Deoxygenated at the Oligosaccharide Level. -The title trisaccharide derivatives are prepared