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Synthesis of fused bicyclic imidazoles by ring-closing metathesis

โœ Scribed by Yingzhong Chen; H.V.Rasika Dias; Carl J. Lovely


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
364 KB
Volume
44
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The preparation of a number of dienylimidazole via chemoselective metal-halogen exchange and their utility in ring-closing metathesis is described. Essentially all regioisomeric permutations participate in metathesis with the notable exception of 4-vinyl-5-allylimidazoles, provided that the imidazole N3 atom is protonated.


๐Ÿ“œ SIMILAR VOLUMES


Ring-closing metathesis for the synthesi
โœ Willem A.L. van Otterlo; E.Lindani Ngidi; E.Mabel Coyanis; Charles B. de Koning ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 136 KB

Ring-closing metathesis (RCM) was used to synthesise five 4H-chromenes, a naphthol and an indenol. These are the first examples of RCM applied to the synthesis of such benzo-fused bicyclic compounds.