Synthesis of fused 1,2,4-thiadiazoles from 5-chloro-1,2,4-thiadiazol-3(2H)-ones
✍ Scribed by Gerrit L'abbé; Johan Buelens; Wim Dehaen; Suzanne Toppet; Janine Feneau-Dupont; Jean-Paul Declercq
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 631 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
Dedicated to Prof. L. Ghosez on the occasion of his 60th birthday
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## Abstract magnified image One‐stage synthesis of 5‐substituted (alkyl, aryl, heteroaryl, arylalkyl, heteroalkyl, alkoxy‐, aryloxy)‐2‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles is described. The compounds were prepared by the reaction of sulfinyl‐bis(2,4‐dihydroxythiobenzoyl) (STB) with hydrazides
hydrates could be air milled, the author proceeded to pnpare suspensions with air-milled hydrate to see if crystal growth still oe curted. Work was done with I-hydrate, because at that time development work on 11 had been discontinued. A 2.5% suspension of air-milled I-hydrate was made (Table ) and