Synthesis of furanoid and pyranoid derivatives of 6-deoxy-4-thio-D-galactose
✍ Scribed by Daniel Cicero; Oscar Varela; Rosa M. De Lederkremer
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 864 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
The synthesis of pyranodd and furanoid derivatives
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Three routes were investigated for the conversion of D-glucose into the title compound. In the first approach, reduction of the 5,6-thiirane ring of 5,6-dideoxy-5,6-epithio-1,2-O-isopropylidene-t~-D-glucofuranose (17) as well as that of its 3-O-allyl derivative (13) with lithium aluminium hydride wa
Dale et al. discussed the role of the hydroxyl groups in the interaction of sugars with the /3-glucosidase by investigating the inhibitory effects of some monosaccharides and their derivatives against the enzyme [1]. We planned to investigate the role of glycon hydroxyl groups via a kinetic study on
## Abstract The ^1^H and ^19^F NMR spectra of the α‐ and β‐pyranose anomers of 4‐deoxy‐4‐fluoro‐D‐glucose (4FG) and 6‐deoxy‐6‐fluoro‐D‐galactose (6FGA) in methanol‐__d__~4~, DMSO‐__d__~6~, acetone‐__d__~6~ and D~2~O solution are reported. Computer analysis of the ABMX spectra of the CHCH~2~F fragm