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Synthesis of Furan-3-carboxylic and 4-Methylene-4,5-dihydrofuran-3-carboxylic Esters by Direct Palladium Iodide Catalyzed Oxidative Carbonylation of 3-Yne-1,2-diol Derivatives

✍ Scribed by Gabriele, Bartolo; Mancuso, Raffaella; Maltese, Vito; Veltri, Lucia; Salerno, Giuseppe


Book ID
115475122
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
657 KB
Volume
77
Category
Article
ISSN
0022-3263

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Palladium-catalyzed oxidative heterocycl
✍ Bartolo Gabriele; Lucia Veltri; Raffaella Mancuso; Pierluigi Plastina; Giuseppe πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 French βš– 223 KB

A novel and convenient approach to furan-3-carboxylic esters 2 is presented, based on palladium-catalyzed direct oxidative carbonylation of readily available 3-yne-1,2-diols 1. The process, corresponding to a sequential combination between a 5-endo-dig heterocyclodehydration step and an oxidative al