## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Functionalized, Unsymmetrical 1,3,4,6-Tetrasubstituted 2,5-Diketopiperazines
✍ Scribed by Tullberg, Marcus; Grøtli, Morten; Luthman, Kristina
- Book ID
- 115454696
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 181 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0022-3263
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Herein we report the efficient syntheses of 1,4-disubstituted-2,3-diketopiperazines and 1,4,5-trisubstituted-2,3-diketopiperazines, which feature a tandem reductive amination and acylation. Aliphatic and aromatic primary amines serve as viable nucleophiles under the mild reaction conditions.