𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Functionalized Pyrazines and Quinoxalines from Nef-Isocyanide Adducts and 1,2-Diamines

✍ Scribed by Issa Yavari; Ramin Pashazadeh; Reza Hosseinpour

Publisher
John Wiley and Sons
Year
2012
Tongue
German
Weight
145 KB
Volume
95
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Alkyl 3‐(alkylamino)‐5,6‐dicyanopyrazine‐2‐carboxylates and alkyl 3‐(alkylamino)quinoxaline‐2‐carboxylates were obtained in good yields by treatment of Nef‐isocyanide adducts with 1,2‐diamines in MeCN.

📜 SIMILAR VOLUMES

1,2,3- and 1,2,4-triazolium salts, pyraz
1,2,3- and 1,2,4-triazolium salts, pyrazoles, and quinoxalines from diarylnitrilimines and isocyanides: A study of the scope
✍ Dietrich Moderhack; Ali Daoud 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 365 KB

## Abstract Formation of the four title compounds has been found to be strongly dependent on substituents: 1,2,3‐Triazolium salts **6** do not arise from nitrilimines **2** that have an electron‐acceptor attached to either the __C__‐ or the __N__‐phenyl group. Likewise __tert__‐butyl and aryl isocy