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Synthesis of four atropdiastereoisomers of C-O-D-O-E ring of vancomycin by sequential cycloetherifications

✍ Scribed by Caroline Vergne; Michèle Bois-Choussy; René Beugelmans; Jieping Zhu

No coin nor oath required. For personal study only.

✦ Synopsis

All four aUuixliastereoisomers of model bicyclic C-O-D-O-E ring of vancomycin have been synthesized by way of sequential SNAr based nmcrocyclization.

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