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Synthesis of fluorine analogues of vitamin e

✍ Scribed by M. Koyama; M. Tamura; M. Hirai; T. Nagal; A. Ando; T. Miki; I. Kumadaki


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
36 KB
Volume
45
Category
Article
ISSN
0022-1139

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## Abstract Vitamin E (VE) analogues, epitomized by α‐tocopheryl succinate (α‐TOS), are proapoptotic agents with selective antineoplastic activity. The molecule of α‐TOS comprises several structurally and functionally distinct moieties that can be modified in order to yield analogues with higher ac