Synthesis of fluorescent methoxy poly(ethylene glycol)-b-Poly(ethyl cyanoacrylate)–2-(N-carbazolyl) ethyl methacrylate copolymer via living oxyanion-initiated polymerization
✍ Scribed by Xiaona Lin; Liandong Deng; Anjie Dong
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 395 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0021-8995
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✦ Synopsis
Abstract
The fluorescent amphiphilic block copolymer methoxy poly(ethylene glycol) (mPEG)‐b‐poly(ethyl cyanoacrylate) (PECA)–2‐(N‐carbazolyl) ethyl methacrylate (CzEMA) was synthesized via living oxyanion‐initiated polymerization. mPEG‐b‐PECA–CzEMA was characterized by gel permeation chromatography, ^1^H‐NMR, and Fourier transform infrared spectroscopy. The results indicate that the polymerization was well controlled with a narrow molecular weight distribution. The mPEG‐b‐PECA–CzEMA nanoparticles prepared by nanoprecipitation techniques showed a narrow size distribution with an average diameter of less than 100 nm. The mPEG‐b‐PECA–CzEMA exhibited a strong carbazole fluorescence. Furthermore, it was found that the fluorescence intensity of mPEG‐b‐PECA–CzEMA was sensitive to a change in solvent. The results indicate that a subtle change in the state of the polymer micellar association may have altered the state of carbazole groups, which was responsible for the fluorescence emission. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012