Synthesis of ethyl 4-oxo-3,4-dihydro[1]benzofuro[3,2-d]-pyrimidine-2-carboxylate and its derivatives
✍ Scribed by Sergey B. Alyabiev; Dmitri V. Kravchenko; Alexandre V. Ivachtchenko
- Book ID
- 108209693
- Publisher
- Royal Society of Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 240 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0959-9436
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📜 SIMILAR VOLUMES
In the crystal structure of the title compound, C 22 H 17 N 3 O 7 , the furo[2,3-d]pyrimidine ring system is essentially planar. -Stacking and intermolecular C-HÁ Á ÁO hydrogen-bond interactions stabilize the crystal structure.
## Abstract Ethyl 3,4‐dihydro‐2__H__‐1,4‐benzoxazine‐3‐carboxylate derivatives **2** were obtained and isolated in low yields from the condensation of 2‐aminophenol and ethyl 2,3‐dibromopropanoate. They can be obtained by hydrogenation of ethyl 2__H__‐1,4‐benzoxazine‐3‐carboxylate in satisfactory y