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Synthesis of ethyl 2-aminodihydro-5-pyrimidinecar-boxylate derivatives and 3,7-diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-1H-pyrimido[1,2-a]pyrimidines

✍ Scribed by René Milcent; Jean-Claude Malanda; Géo Barbier; Jacqueline Vaissermann


Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
440 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Reactions of ethyl 3‐aryl‐2‐benzoylpropenoates 1 with guanidine and N‐alkyl(or benzyl)guanidines have been investigated. Ethyl 2‐aminodihydro‐5‐pyrimidinecarboxylate derivatives 3, 4 or 5, and 3,7‐diethoxy‐carbonyl‐4,6‐dihydro‐2,4,6,8‐tetraaryl‐1__H__‐pyrimido[1,2‐a]pyrimidines 6 have been synthesized.


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9,9′-Thiobis-(1,2,3,4,7,8-hexahydro-7-me
✍ Ondrej Šimo; Alfonz Rybár; Juraj Alföldi; Vladimír Pätoprstý 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 292 KB

## Abstract The 6‐(3‐hydroxypropylamino)‐3‐methylpyrimidine‐2,4‐dione (1) did not afford the expected 6‐(3‐chloro‐propylamino)‐ derivative on reaction with thionyl chloride, but, instead, the pyrimidine rings were joined __via__ a sulfur bridge to give 9,9′‐thiobis(1,2,3,4,7,8‐hexahydro‐7‐melnyl‐6_