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Synthesis of epimeric 15-hydroxyestriols, new and potential metabolites of estradiol

โœ Scribed by Fishman, Jack; Guzik, Henry


Book ID
120335857
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
457 KB
Volume
33
Category
Article
ISSN
0022-3263

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Synthesis of estra-1,3,5(10)-trien-3,15ฮฑ
โœ Jack Fishman; Henry Guzik ๐Ÿ“‚ Article ๐Ÿ“… 1967 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 162 KB

A new metabolite derived from estradiol and considered to be exclusively fetal in origin was obtained from neonatal and pregnancy urine by Hagen et al' and Gurpide et a12. The compound contained four acylable hydroxy functions and formed an acetonide derivative. One tentative structure suggested was