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Synthesis of (endo) 3,9-disubstituted diazabicyclo[3.3.1]nonan-7-amines

✍ Scribed by J.A. Gregory; A.J. Jennings; G.F. Joiner; F.D. King; S.K. Rahman


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
201 KB
Volume
36
Category
Article
ISSN
0040-4039

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Synthesis and Stereochemistry of 7,9-Dis
✍ Nemes, Peter ;Janke, Frank ;Scheiber, PΓ‘l πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 406 KB

## Abstract The azabicyclic __endo__ compound 3 was synthesized by reaction of enamine 1 with 2‐benzoyl‐1,3‐dichloropropane (2). The thermodynamically more stable __exo__ isomer 4 was obtained by epimerization of 3 with sodium methoxide. The reduction of 3 and 4 was carried out with different reduc