Synthesis of Enantiopure Chloroalcohols by Enzymatic Kinetic Resolution.
β Scribed by Robert M. Haak; Chiara Tarabiono; Dick B. Janssen; Adriaan J. Minnaard; Johannes G. de Vries; Ben L. Feringa
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 22 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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A kinetic model for -transaminase from Bacillus thuringiensis JS64 was developed by using the King- Altman method to simulate the kinetic resolution of β£methylbenzylamine (β£-MBA). Starting from a ping-pong bi-bi mechanism, a complete kinetic model including substrate inhibition only in the reverse r