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Synthesis of enantiopure 3-hydroxymethylchromanes via intramolecular nitrone cycloaddition

✍ Scribed by Gianluigi Broggini; Franco Folcio; Nicola Sardone; Milko Sonzogni; Gaetano Zecchi


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
495 KB
Volume
7
Category
Article
ISSN
0957-4166

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πŸ“œ SIMILAR VOLUMES


Rapid entry to enantiopure polycyclic Ξ²-
✍ Benito Alcaide; Jose M. Alonso; Moustafa F. Aly; Elena SΓ‘ez; M. Paz MartΓ­nez-Alc πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 286 KB

New enantiomerically pure fused 2 or bridged 3 polycyclic 15-1actam systems are regio-and stereoselectively prepared via intramolecular nitrone-alkene cycloaddition of 2azetidinone-tethered alkenyl-aldehydes 1. The regioselectivity of the cycloaddition can be tuned by moving the alkene substituent f