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Synthesis of enantiopure 2-aryl-2-methoxypropionic acids and determination of their absolute configurations by X-ray crystallography

✍ Scribed by Satoshi Sekiguchi; Junpei Naito; Hiromi Taji; Yusuke Kasai; Akinori Sugio; Shunsuke Kuwahara; Masataka Watanabe; Nobuyuki Harada


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
337 KB
Volume
20
Category
Article
ISSN
0899-0042

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## Abstract Straightforward syntheses of enantiopure __N__‐benzoyl‐ and __N__‐__tert__‐butyloxycarbonyl‐protected sulfonimidamides, which can be used as building blocks in newly designed catalysts, are presented. Key synthetic step is a dynamic resolution of a racemic sulfinic acid sodium salt. All