Synthesis of enantiopure 1,2-diamine attached to cross-linked polystyrene and its application to an insoluble catalyst for asymmetric hydrogenation

✍ Scribed by Shinichi Itsuno; Atsushi Tsuji; Miyuki Takahashi

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 171 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00742-1

✦ Synopsis

A novel enantiopure 1,2-diamine (5) having two phenolic hydroxy groups was attached into chloromethylated polystyrene through benzyl ether linkage, which was used as a chiral ligand of the catalyst in asymmetric hydrogenation of acetophenone.