𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors

✍ Scribed by Moure, Alejandra; Orzáez, Mar; Sancho, Mónica; Messeguer, Angel


Book ID
122372184
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
319 KB
Volume
22
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Solid-phase synthesis of 3,7-disubstitut
✍ Jérôme Giovannoni; Gilles Subra; Muriel Amblard; Jean Martinez 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 71 KB

We report here the synthesis of 3,7-disubstituted perhydro-1,4-diazepine-2,5-diones from amino acids and b-amino acids using a backbone amide linker (BAL) as a cis-configuration inductor. We have optimized each steps of the synthesis on solid support using Mimotopes crowns.