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Synthesis of Enantiomerically Pure Highly Functionalized Furanoid Glycal and 2,5-Dihydrofuran Building Blocks

✍ Scribed by Pinki Pal; Brijesh Kumar; Arun K. Shaw


Book ID
102177058
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
193 KB
Volume
2009
Category
Article
ISSN
1434-193X

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An efficient protocol for stereo-and regiocontrolled synthesis of small polyfunctional molecules is presented. The stereospecific addition of PhSeCI to 2,5-dihydro-2,5-dimethoxy-furan 1 in solvents, such as methylene chloride and methanol, gives cyclic and linear acetals 2 and 3, depending on the so