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Synthesis of enantiomeric pureCis-dichloroplatinum(II) amino acid complexes

โœ Scribed by Demetrios Dalietos; Arthur Furst; Dimitrios Theodoropoulos

Book ID
112893198
Publisher
Humana Press Inc
Year
1982
Tongue
English
Weight
257 KB
Volume
4
Category
Article
ISSN
0163-4984

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Enantiomerically pure 1, 2-diamino-1-(4-fluorophenyl)propanes were synthesized by stereospecific and stereoselective procedures by use of the (1R, 2S)- and (1S, 2R)-2-amino-1-(4-fluorophenyl)propanols (12a) as intermediates. The enantiomeric purity was determined by (1)H NMR spectroscopy after conve