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Synthesis of (E)- and (Z)-fluoro-olefin analogues of potent dipeptidyl peptidase IV inhibitors

✍ Scribed by Pieter Van der Veken; István Kertèsz; Kristel Senten; Achiel Haemers; Koen Augustyns


Book ID
104254156
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
142 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis


Horner-Emmons reaction, followed by amide formation and reduction of the amide were used for the construction of the a-fluoro-a,b-unsaturated amine functionality.


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