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Synthesis of dithia- and tetrathiacyclophanes incorporating isoxazole units

✍ Scribed by Taizo Hatta; Muneob Kawano; Hironori Maeda; Otohiko Tsuge


Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
339 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The reaction of 5‐bromomethyl‐3‐(p‐bromomethylphenyl)isoxazole with o‐, m‐, and p‐bis(mercap‐tomethyl)benzenes gave the corresponding dithia‐ and/or tetrathiaisoxazolophanes, whose relative yields strongly depended upon the nature of the mercaptomethyl compound. The above isoxazole dibromide reacted with the bis(mercaptomethyl)isoxazole to afford a mixture of two isomeric dithiaisoxazolophanes.


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