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Synthesis of Dimeric Acridine Derived Antivirals.

✍ Scribed by Rene Csuk; Alexander Barthel; Torsten Brezesinski; Christian Raschke

Publisher
John Wiley and Sons
Year
2005
Weight
95 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract We use one molecule of ethylene diamine as a connecting arm to combine two molecules of 5,6‐dehydronorcantharidin. Then, ten novel norcantharidin derivatives were synthesized in a single step by the [3 + 2] 1,3‐dipolar cycloaddition reaction with oxime or hydrazone in the presence of ch