## Abstract __Cyclo__(D‐Leu‐L‐Leu) and __cyclo__(L‐Leu‐L‐Leu) were synthesized, and their carbon‐13 nmr spectra at 65 MHz were examined in dimethylsulfoxide and trifluoroacetic acid solutions. The chemical shift data are consistent with a boat or “twisted” boat conformation of the diketopiperazine
Synthesis of Diketopiperazines Containing Prolinyl Unit — Cyclo(L-prolinyl-L-leucine), Cyclo(L-prolinyl-L-isoleucine) and Cyclo(L-tryptophyl-L-proline).
✍ Scribed by S. Jhaumeer-Laulloo; A. Khodabocus; A. Jugoo; D. Jheengut; S. Sobha
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 78 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The crystal and molecular structures of two α‐aminoisobutyric acid (Aib)‐containing diketopiperazines, cyclo(Aib‐Aib) 1 and cyclo(Aib‐L‐Ile) **2**, are reported. Cyclo(Aib‐Aib) crystallizes in the space group P1 with __a__ = 5.649(3), __b__ = 5.865(2), __c__ = 8.363(1), α = 69.89(6), β
## Abstract The crystal structure and conformation of the synthetic cyclic tetrapeptide, __cyclo__(L‐Pro‐Sar)~2~, was determined by x‐ray analysis. The peptide crystallizes in the orthorhombic space group __P__2~1~2~1~2~1~ with cell parameters __a__ = 9.277(1), __b__ = 12.884(1), and __c__ = 15.581