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Synthesis of “dihydroacarbose”, a potent α-d-glucosidase inhibitor

✍ Scribed by Mitsuo Hayashida; Nobuo Sakairi; Hiroyoshi Kuzuhara


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
375 KB
Volume
158
Category
Article
ISSN
0008-6215

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Synthesis of “dihydroacarbose”, an α-d-g
✍ Mitsuo Hayashida; Nobuo Sakairi; Hiroyoshi Kuzuhara; Motoyuki Yajima 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 977 KB

"Dihydroacarbose" (2), an alpha-D-glucosidase inhibitor having a pseudo-tetrasaccharide structure, was synthesized by reductive coupling of 4(3)-amino-1(1),6(1)-anhydro-2(1),3(1),2(2),3(2),6(2),2(3),3(3)-hepta-O- benzyl-4(3),6(3)-dideoxy-beta-maltotriose and 2D-(2,4/3,5)-2,3,4-tris(benzyloxy)-5-(tri