Three types of novel triptolide analogues with 9,11-olefin (3-5), five-membered unsaturated lactam ring (6-7) or A/B cis ring junction (8-14) were synthesized. Although with 9,11-olefin instead of 9,11-Ξ²-epoxide, compound 4a was much more active than the parent natural triptolide (1) with the lowest
β¦ LIBER β¦
Synthesis of Desthio Prenylcysteine Analogues: Sulfur Is Important for Biological Activity.
β Scribed by Brian S. Henriksen; Jessica L. Anderson; Christine A. Hrycyna; Richard A. Gibbs
- Book ID
- 101983605
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 20 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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