Synthesis of derivatives of 1,3-dihydrospiro[2h-indole-2,2′-pyrrolidine]
✍ Scribed by A. A. Shachkus; Yu. A. Degutis; P. P. Mikul'skis
- Book ID
- 104781507
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 349 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0009-3122
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Depending on the experimental conditions the spirolactone **3** on treatment with methylamine gave compounds **6, 7** or the rearranged product **4**. Compound **4** was used to prepare the title compounds **11–13, 15, 18–20** and other derivatives.
In the title compound, C 26 H 20 BrN 3 O 3 , the central pyrrolidine ring adopts an envelope conformation. In the crystal structure, the molecules exist as centrosymmetric N-HÁ Á ÁO hydrogenbonded dimers. The dimers are linked via C-HÁ Á ÁO hydrogen bonds, forming a chain along the b axis.