Synthesis of dendritic stationary phases with surface-bonded L-phenylalanine derivate as chiral selector and their evaluation in HPLC resolution of racemic compounds

(S)-Leucine and [(S)-1-(1-Naphthyl)ethyl

(S)-Leucine and [(S)-1-(1-Naphthyl)ethyl]amine as Chiral Building Blocks for a Bifunctional System − Synthesis of a New Chiral Stationary Phase and Evaluation of Its Biselector Properties in the HPLC Resolution of Racemic Compounds

✍ Anna Iuliano; Emanuele Attolino; Piero Salvadori 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 295 KB 👁 3 views

Two selectors derived from [(S)-1-(1-naphthyl)ethyl]amine and (S)-leucine have been chemically bonded to one another and the resulting chiral auxiliary linked covalently to silica gel, to produce a new chiral stationary phase (CSP) for the HPLC resolution of enantiomers. The CSP is able to separate