✦ LIBER ✦
Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
✍ Scribed by Ramon Eritja; Anna Pons; Mónica Escarcellar; Ernest Giralt; Fernando Albericio
- Book ID
- 104203990
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 618 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
Oligonucleotide-peptide hybrid molecules containing a nuclear transport signal have been synthesized using two different approaches based on the specific reactivity of the thiol group.
The use of oligodeoxynucleotides to specifically inhibit gene expression through intracellular hybridization was first reported some years ago by P.