Taking advantage of the high functionality of an enantiopure protected syn-2R-amino-l,3,4-triol derivative, easily available on a multigram scale from Disoascorbic acid, several biologically active compounds have been synthesized such as the (2S,3R)-3-amino-2-hydroxydecanoic acid (AHDA), the N-termi
Synthesis of d-camphor based γ-amino acid (1S,3R)-3-amino-2,2,3-trimethylcyclopentane carboxylic acid
✍ Scribed by Joel B. Eagles; Shawn R. Hitchcock
- Book ID
- 108284554
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 407 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
The litle anlinomethyl (5) and amino (6) alcohols, which are of interest as intermediates in the synthesis of carbocyclic analogues of nucleosides, were prepared from (+)-camphoric acid via methyl (1S,3R)-3-carbamoyl-2.3.3-trimelhylcyclopel~tane earboxylale (8). Direct reduction of S gave 5 in 26% y
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