Synthesis of cyclopentane-containing marine eicosanoid bacillariolide II

✍ Scribed by Hiroaki Miyaoka; Masahide Tamura; Yasuji Yamada

• Book ID: 104258567
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 223 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10660-8

✦ Synopsis

Marine eieosanoid bacillariolide II was synthesized from (R)-malic acid, involving the diastereoselective one-pot formation of chiral cyclopentane derivative 12 from the anion of allyl phenyl snlfone and chiral epoxymesylate 11 as the key step.