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Synthesis of corticosteroid derivatives containing the 20.beta.-Ol-21-al side chain

โœ Scribed by Oh, Sea-Wha.; Monder, Carl.

Book ID
121382791
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
613 KB
Volume
41
Category
Article
ISSN
0022-3263

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Corticosteroids and related compounds containing the 20-keto-21-hydroxyl side chain such as betamethasone, betamethasone 9,11-epoxide, dexamethasone, and dexamethasone 9,11-epoxide have been found to undergo facile autooxidation on the 1,3-dihydroxyacetone side chain of their D-rings under strong al