Synthesis of corey lactone via highly stereoselective asymmetric diels-alder reaction
β Scribed by Katsuaki Miyaji; Yoshio Ohara; Yasuhiro Takahashi; Toshihiko Tsuruda; Kazutaka Arai
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 142 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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Cis-9,10-dihydro-9,10-ethanoanthracene-11-12-dicarboxylic acid anhydride (1) was converted into its amic acid derivative by reaction with L-leucine. The cyclization reaction was carried out in situ using triethylamine to give the succinic imide-acid derivative (2). Compound (2) was converted to the