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Synthesis of condensed tricyclic pyrazolo[3,4-b]thieno[2,3-d]pyridine and related isostere derivatives

✍ Scribed by Alcione S. De Carvalho; Carlos A. M. Fraga; Eliezer J. Barreiro


Book ID
112131469
Publisher
Journal of Heterocyclic Chemistry
Year
1996
Tongue
English
Weight
284 KB
Volume
33
Category
Article
ISSN
0022-152X

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Synthesis of some new bipyridines, thien
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## Abstract Cyclocondensation of cyanoacetamide and cyanothioacetamide with sodium salt of 3‐hydroxy‐1‐(pyridin‐3‐yl)prop‐2‐en‐1‐one gave 6‐oxo‐[2,3β€²]bipyridine **5a** and 6‐thioxo‐[2,3β€²]bipyridine **5b** derivatives, respectively. Compound **5b** upon treatment with different methylenes **8** gave