Synthesis of chiral trans-anti-trans-isomers of dicyclohexano-18-crown-6 via an enzymatic reaction and the solid-state structure of one enantiomer

✍ Scribed by Kazuhiro Yamato; Richard A. Bartsch; Grant A. Broker; Robin D. Rogers; Mark L. Dietz

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 232 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01187-5

✦ Synopsis

Chiral trans-anti-trans-dicyclohexano-18-crown-6

isomers are synthesized via a lipase-catalyzed reaction. The solidstate structure of the (S)-enantiomer is determined and compared with those reported for 18-crown-6 and trans-syn-trans-dicyclohexano-18-crown-6.