Synthesis of chiral, densely functionalized medium-sized rings from carbohydrate precursors via regioselective exo/endo-primary alkyl radical cyclizations

✍ Scribed by José Marco-Contelles; Elsa de Opazo

• Book ID: 104210515
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 134 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00837-6

✦ Synopsis

The ®rst 8-endo-trig and 7-exo-dig carbocyclizations of primary alkyl free radicals on acyclic carbohydrate templates derived from d-glucose, leading to chiral and polyfunctionalized medium-sized carbocycles are described.