An efficient and convergent route toward
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Tapes Bhattacharyya; Ulf J Nilsson
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Article
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2001
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Elsevier Science
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French
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A practical procedure for the synthesis of water-soluble, chiral and amphiphilic macrocyclic molecules is described. Acylation of p-xylylene diamine with Fmoc-protected glycine and aspartic acid, followed by removal of the Fmoc moiety afforded amino acid:p-xylene conjugates as free diamines. These d