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Synthesis of ceramic-polymer-drug biocomposites at room temperature

✍ Scribed by M. Vallet-Regí; M. Gordo; C.V. Ragel; M.Y. Cabañas; J.San Román

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
509 KB
Volume
101-103
Category
Article
ISSN
0167-2738

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✦ Synopsis

The preparation of hard composites by the free radical polymerization at room temperature of a blend of p-tricalcium phosphate, poly(ethy1 methacrylate), methyl methacrylate monomer and fosfosalB is described. After the immersion of the composites in a buffered solution, the controlled release of an analgesic drug, fosfosal, is observed. The ceramic component participates actively in the control of the release of the drug by means of the formation of a bridging complex with the fosfosal, as demonstrated by FTIR studies.

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