Synthesis of Carbazole, Acridine, Phenazine, 4H-Benzo[def]carbazole and Their Derivatives by Thermal Cyclization Reaction of Aromatic Amines.

Synthesis of carbazole, acridine, phenaz

Synthesis of carbazole, acridine, phenazine, 4H-benzo[def]carbazole and their derivatives by thermal cyclization reaction of aromatic amines

✍ Takaaki Horaguchi; Takako Oyanagi; Evelyn Cuevas Creencia; Kiyoshi Tanemura; Tsu 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 209 KB

## Abstract A variety of nitrogen‐containing heterocycles were synthesized by passing vapors of aromatic amines over calcium oxide at 450–650 °C under nitrogen carrier gas. Reaction of 2‐aminobiphenyl 3a at 560 °C gave carbazole 4 in 80% yield. Reaction of 2, 2′‐diaminobiphenyl 3b afforded a mixtur