Synthesis of C2-symmetric 1,4-diketones from tartaric acid dichloride
β Scribed by Francesco Babudri; Vito Fiandanese; Giuseppe Marchese; Angela Punzi
- Book ID
- 108187766
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 195 KB
- Volume
- 689
- Category
- Article
- ISSN
- 0022-328X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
methyl protecting groups (BBr,, CHCI,) then gave l a in 70 % yield. The 'H and 13C NMR spectra of 1 a (in D,O/ NaOD) and of 1 b (in CDC1,) reflect the symmetry of the molecules. The methoxyl groups are magnetically equivalent in 1 b, but in the open-chain triester precursor 2b, two
Homochiral l-alkyl-3,4-dihydroxypyrrolidines, (S,S)-and (R,R)-5 were obtained by cyclization and reduction of both enantiomers of (+)-and (-)-tartaric acid, respectively. Also (S,S)-3,4-dihydroxytetrahydrofurane 6 was prepared from (+)-diethyl tartrate. All these heterocyclic vic-diols underwent two