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Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors

✍ Scribed by Hongqing Li; Yongmin Zhang; Sylvain Favre; Pierre Vogel; Matthieu Sollogoub; Yves Blériot

Book ID
113515429
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
581 KB
Volume
356
Category
Article
ISSN
0008-6215

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✍ Miroslav Terinek; Andrea Vasella 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 154 KB 👁 1 views

## Abstract The __gluco__‐configured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __β__‐amino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an