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Synthesis of Branched Polyglucans by the Tandem Action of Potato Phosphorylase and Deinococcus geothermalis Glycogen Branching Enzyme

✍ Scribed by Jeroen van der Vlist; Marta Palomo Reixach; Marc van der Maarel; Lubbert Dijkhuizen; Arend Jan Schouten; Katja Loos


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
194 KB
Volume
29
Category
Article
ISSN
1022-1336

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✦ Synopsis


Abstract

An enzymatic tandem reaction is described in which the enzymes phosphorylase and Deinococcus geothermalis glycogen branching enzyme (Dg GBE) catalyze the synthesis of branched polyglucans from glucose‐1‐phosphate (G‐1‐P). Phosphorylase consumes G‐1‐P and polymerizes linear amylose while Dg GBE introduces branching points on the α‐(1 → 6) positions by reshuffling short oligosaccharides. The resulting branched polyglucans have an unusually high degree of branching of 11%.

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