Improved production of recombinant human
✍
Tomoshi Ohya; Tetsuji Hayashi; Eriko Kiyama; Hiroko Nishii; Hideo Miki; Kaoru Ko
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 260 KB
👁 2 views
## Abstract To improve the production of recombinant human antithrombin III (AT‐III) in Chinese hamster ovary (CHO) cells, the genes encoding transcription factors, ATF4 (activating transcription factor 4) and XBP‐1s (the spliced form of X‐box binding protein 1), which were involved in the mammalia