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Synthesis of bipyrazoles and pyrazoloisoxazoles from 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

✍ Scribed by Abderrahman Bendaas; Maâmar Hamdi; Nicole Sellier


Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
249 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Phenylhydrazine or hydrazine react with 3‐acetyl‐4‐hydroxy‐6‐methyl‐2__H__‐pyran‐2‐one (1) to give 4‐acetoacetyl‐3‐methylpyrazolin‐5‐ones 4. The synthesis of bipyrazoles and pyrazoloisoxazoles from 4 are reported.


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New synthesis and reactivity of 3-bromoa
✍ Djamila Hikem-Oukacha; Maamar Hamdi; Artur M. S. Silva; Rachedi Yahia 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 137 KB

## Abstract 3‐(Bromoacetyl)‐4‐hydroxy‐6‐methyl‐2__H__‐pyran‐2‐one was synthesized by the reaction of dehydroacetic acid (DHAA) with bromine in glacial acetic acid. Novel heterocyclic products were synthesized from the reaction of bromo‐DHAA with alkanediamines, phenylhydrazines, __ortho__‐phenylene