Synthesis of non-natural glycosylamino a
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Stacy J Keding; Atsushi Endo; Samuel J Danishefsky
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Article
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2003
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Elsevier Science
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French
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The synthesis of biologically relevant glycosylamino acids using a non-natural amino acid as the glycosyl acceptor is described. The glycosylation reaction of a monosaccharide tri-chloroacetimidate donor with Fmoc-L-hydroxynorleucine benzyl ester provided the a-Olinked product. Conversely, when the