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Synthesis of biologically active carbocyclic analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP)

✍ Scribed by Barton, Derek H. R.; Camara, Jose; Dalko, Peter; Gero, Stephen D.; Quiclet-Sire, Beatrice; Stuetz, Peter


Book ID
127351739
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
302 KB
Volume
54
Category
Article
ISSN
0022-3263

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Synthesis of acyclic analogs ofN-acetylm
✍ Danklmaier, Johann ;HΓΌnig, Helmut πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 665 KB

## Abstract The syntheses of the acyclic MDP analogs 27–37 is described, the carbohydrate moiety of muramic acid being replaced by acyclic amino alcohol structures. Their preparation was accomplished by hydrolytic cleavage of the cyclic, disubstituted 3‐morpholinones 2–5 and protection of the free